Preheat oven to 350°F (175°C).

In a large skillet over medium heat, brown the ground beef until fully cooked, breaking it apart as it cooks. Drain excess fat.

In a large bowl, combine the ground beef, green beans, cream of mushroom soup, milk, garlic powder, onion powder, salt, and pepper. Mix well.

Spread the mixture evenly into a greased 9×13-inch baking dish.

Sprinkle the shredded cheddar cheese evenly over the top.

Bake for 25 minutes, until the casserole is hot and bubbly and the cheese is melted.

Remove from the oven, sprinkle French fried onions on top, and bake for an additional 5–10 minutes until the onions are golden and crisp.